Year: 2017 | Month: June | Volume 7 | Issue 3
Gross and Histomorphological Studies of Liver in Neonatal Rabbit (Oryctolagus cuniculus)
Abstract:
Rabbit is a laboratory animal and is used to conduct wide variety of experiments for the welfare of human as well as animals. Liver is the main organ of metabolism and study of xenobiotics is usually carried out in this particular organ. The present study was conducted on six rabbits (non-descript) between 0-3 days of age, procured from laboratory of department of Microbiology, college of Veterinary Science & A.H. Jabalpur. The liver was carefully dissected out and fixed in 10% formalin. After gross measurements tissue samples were processed and 5-6 μm thick paraffin sections were stained with Haematoxylin and Eosin stain and silver impregnation method for histological studies. Mean weight, length, width and height of liver were 16.30±0.37gm, 2.52±0.05 cm, 2.15 ±0.04 cm and 1.07 ±0.03cm respectively. The liver was comprised of two main lobes, right and left, that are separated by a deep median cleft. There were five lobes viz., Left Lateral, Left Medial, Right, Caudate and Quadrate lobes. The extent of the caudate process was bigger than that of the papillary process and the smallest structure in length and height was quadrate lobe. Histologically Mitoses was observed in the liver cells. The cell outline was indistinct and cytoplasm showed extreme variation in appearance as vacuolated, granular, deep staining or pale. There was presence of haematopoietic cells (megakaryocytes) in the stroma of liver.
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